Xavier Hernandez-Alias


2023 - present

EMBO Postdoctoral Fellow in the groups at the Max-Planck-Institute of Biochemistry (MPIB) and at the Chair of Computational Molecular Medicine, TUM, Germany


Collaboratory Professor at the Universitat Oberta de Catalunya (UOC) Barcelona, Spain

2023 Postdoc in the group of Prof. Luis Serrano at the Centre for Genomic Regulation, Barcelona, Spain
2018 - 2023 PhD student at the Centre for Genomic Regulation (Prof. Luis Serrano and Dr. Martin Schaefer), Barcelona, Spain


2018 - 2023 Ph.D. in Biomedicine (Systems Biology) at the Centre for Genomic Regulation (CRG) Barcelona, Spain
2016 - 2018 M.Sc. in Biology (Major in Systems Biology) at the ETH Zürich, Switzerland
2012 - 2016 B.Sc. in Biochemistry, University of Barcelona (UB), Spain


  • Xavier Hernandez-Alias@, Hannah Benisty, Leandro G. Radusky, Luis Serrano@, Martin H. Schaefer@. Using protein-per-mRNA differences among human tissues in codon optimization. Genome Biology, 2023.
  • Xavier Hernandez-Alias, Christopher D. Katanski, …, Martin H. Schaefer, Luis Serrano, Tao Pan@. Single-molecule tRNA-seq analysis reveals coordination of tRNA modification and charging and fragmentation. Nucleic Acids Research, 2023.
  • Hannah Benisty@, Xavier Hernandez-Alias, Marc Weber, Miquel Anglada-Girotto, …, Martin H. Schaefer, Luis Serrano@. Genes enriched in A/T-ending codons are co-regulated and conserved across mammals. Cell Systems, 2023.
  • Xavier Hernandez-Alias@, Hannah Benisty, Martin H. Schaefer@, Luis Serrano@. Translational adaptation of human viruses to the tissues they infect. Cell Reports, 2021.
  • Sarah A. Head@, Xavier Hernandez-Alias, Jae-Song Yang, Ludovica Ciampi, Violeta Beltran-Sastre, Antonio Torres-Méndez, Manuel Irimia, Martin H. Schaefer@, Luis Serrano@. Silencing of SRRM4 suppresses microexon inclusion and promotes tumor growth across cancers. PLOS Biology, 2021.
  • Josep Tarragó-Celada*, Carles Foguet*, …, Xavier Hernandez-Alias, …, Marta Cascante@. Cysteine and Folate Metabolism Are Targetable Vulnerabilities of Metastatic Colorectal Cancer. Cancers, 2021.
  • Javier Delgado Blanco, Xavier Hernandez-Alias, Damiano Cianferoni, Luis Serrano@. In silico mutagenesis of human ACE2 with S protein and translational efficiency explain SARS-CoV-2 infectivity in different species. PLOS Computational Biology, 2020.
  • Hannah Benisty, Marc Weber, Xavier Hernandez-Alias, Martin H. Schaefer@, Luis Serrano@. Mutation bias within oncogene families is related to proliferation-specific codon usage. Proc Natl Acad Sci USA, 2020.
  • Ritobrata Ghose@, …, Xavier Hernandez-Alias, et al. From research to rapid response: mass COVID-19 testing by volunteers at the Centre for Genomic Regulation. F1000Research, 2020.
  • Xavier Hernandez-Alias, Hannah Benisty, Martin H. Schaefer, Luis Serrano@. Translational efficiency across healthy and tumor tissues is proliferation-related. Molecular Systems Biology, 2020.